Coenzym Q10
Ubichinon
Ubichinol 
(bioaktive Form)

Wirkungen

Q10 neutralisiert freie Radikale und schleust deren freie Elektronen in die Elektronentransportkette der Mitochondrien zur Energiegewinnung ein.
Schützt insbesondere vor Hydroxylradikalen.

Inhalt umschalten
Inhalt umschalten

Ursachen eines Q10-Mangels

  • Statine (Cholesterinsenker)
  • ß-Blocker
  • einige Antidiabetika
  • trizyklische Antidepressiva

Der Verzicht auf Fleisch führt oft zu kritisch niedrigen Werten an Coenzym Q10 und Carnitin.

Indikationen zur Substitution

⇒ 200mg Ubichinol tgl.


Quellen:
Moreno-Fernandez J, Puche-Juarez M, Toledano JM, et al. Ubiquinol Short-Term Supplementation Prior to Strenuous Exercise Improves Physical Performance and Diminishes Muscle Damage. Antioxidants (Basel). 2023;12(6):1193. Published 2023 May 31. doi:10.3390/antiox12061193


Quellen:
Sumbalová Z, Kucharská J, Rausová Z, et al. Reduced platelet mitochondrial respiration and oxidative phosphorylation in patients with post COVID-19 syndrome are regenerated after spa rehabilitation and targeted ubiquinol therapy. Front Mol Biosci. 2022;9:1016352. Published 2022 Oct 21. doi:10.3389/fmolb.2022.1016352


Quellen: Gvozdjáková A, Kucharská J, Ostatníková D, Babinská K, Nakládal D, Crane FL. Ubiquinol improves symptoms in children with autism. Oxid Med Cell Longev. 2014;2014:798957. doi:10.1155/2014/798957


Quellen:
García-Carpintero S, Domínguez-Bértalo J, Pedrero-Prieto C, et al. Ubiquinol Supplementation Improves Gender-Dependent Cerebral Vasoreactivity and Ameliorates Chronic Inflammation and Endothelial Dysfunction in Patients with Mild Cognitive Impairment. Antioxidants (Basel). 2021;10(2):143. Published 2021 Jan 20. doi:10.3390/antiox10020143

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Quellen:
Onur S, Niklowitz P, Jacobs G, et al. Ubiquinol reduces gamma glutamyltransferase as a marker of oxidative stress in humans. BMC Res Notes. 2014;7:427. Published 2014 Jul 4. doi:10.1186/1756-0500-7-427

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Quellen:
Onur S, Niklowitz P, Jacobs G, et al. Ubiquinol reduces gamma glutamyltransferase as a marker of oxidative stress in humans. BMC Res Notes. 2014;7:427. Published 2014 Jul 4. doi:10.1186/1756-0500-7-427

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Quellen:
Thakur AS, Littarru GP, Funahashi I, Painkara US, Dange NS, Chauhan P. Effect of Ubiquinol Therapy on Sperm Parameters and Serum Testosterone Levels in Oligoasthenozoospermic Infertile Men. J Clin Diagn Res. 2015;9(9):BC01-BC3. doi:10.7860/JCDR/2015/13617.6424

CoQ10 deficiency has been suggested as a factor in complications of hyperthyroidism, including heart failure. Pre-clinical research and a small clinical study indicate CoQ10 supplementation may help improve cardiac performance in those with hyperthyroidism [,,].


Quellen:
Mantle D, Hargreaves IP. Coenzyme Q10 and Endocrine Disorders: An Overview. Antioxidants (Basel). 2023;12(2):514. Published 2023 Feb 17. doi:10.3390/antiox12020514


Quellen:
Mantle D, Hargreaves IP. Coenzyme Q10 and Endocrine Disorders: An Overview. Antioxidants (Basel). 2023;12(2):514. Published 2023 Feb 17. doi:10.3390/antiox12020514


Quellen:
Mantle D, Hargreaves IP. Coenzyme Q10 and Endocrine Disorders: An Overview. Antioxidants (Basel). 2023;12(2):514. Published 2023 Feb 17. doi:10.3390/antiox12020514


Quellen:
Mantle D, Hargreaves IP. Coenzyme Q10 and Endocrine Disorders: An Overview. Antioxidants (Basel). 2023;12(2):514. Published 2023 Feb 17. doi:10.3390/antiox12020514

⇒ 100-200mg Ubichinol tgl.

Quellen:

  • Mantle D, Hargreaves IP. Coenzyme Q10 and Endocrine Disorders: An Overview. Antioxidants (Basel). 2023;12(2):514. Published 2023 Feb 17. doi:10.3390/antiox12020514
  • Palan P.R., Connell K., Ramirez E., Inegbenijie C., Gavara R.Y., Ouseph J.A., Mikhail M.S. Effects of menopause and hormone replacement therapy on serum levels of coenzyme Q10 and other lipid-soluble antioxidants. Biofactors. 2005;25:61–66. doi: 10.1002/biof.5520250107. [PubMed] [CrossRef] [Google Scholar]

⇒ 100mg Ubichinol tgl.


Quellen:

⇒ 50-100mg Ubichinol tgl.


Quellen: