6. Januar 2024

Wirkungen

Q10 neutralisiert freie Radikale und schleust deren freie Elektronen in die Elektronentransportkette der Mitochondrien zur Energiegewinnung ein.

Ursachen eines Q10-Mangels

  • Statine (Cholesterinsenker)
  • ß-Blocker
  • einige Antidiabetika
  • trizyklische Antidepressiva

Der Verzicht auf Fleisch führt oft zu kritisch niedrigen Werten an Coenzym Q10 und Carnitin.

Indikationen zur Substitution

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⇒ 200mg Ubichinol tgl.

Quellen:
Moreno-Fernandez J, Puche-Juarez M, Toledano JM, et al. Ubiquinol Short-Term Supplementation Prior to Strenuous Exercise Improves Physical Performance and Diminishes Muscle Damage. Antioxidants (Basel). 2023;12(6):1193. Published 2023 May 31. doi:10.3390/antiox12061193

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Quellen:
Sumbalová Z, Kucharská J, Rausová Z, et al. Reduced platelet mitochondrial respiration and oxidative phosphorylation in patients with post COVID-19 syndrome are regenerated after spa rehabilitation and targeted ubiquinol therapy. Front Mol Biosci. 2022;9:1016352. Published 2022 Oct 21. doi:10.3389/fmolb.2022.1016352

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Quellen: Gvozdjáková A, Kucharská J, Ostatníková D, Babinská K, Nakládal D, Crane FL. Ubiquinol improves symptoms in children with autism. Oxid Med Cell Longev. 2014;2014:798957. doi:10.1155/2014/798957

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Quellen:
García-Carpintero S, Domínguez-Bértalo J, Pedrero-Prieto C, et al. Ubiquinol Supplementation Improves Gender-Dependent Cerebral Vasoreactivity and Ameliorates Chronic Inflammation and Endothelial Dysfunction in Patients with Mild Cognitive Impairment. Antioxidants (Basel). 2021;10(2):143. Published 2021 Jan 20. doi:10.3390/antiox10020143

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Quellen:
Onur S, Niklowitz P, Jacobs G, et al. Ubiquinol reduces gamma glutamyltransferase as a marker of oxidative stress in humans. BMC Res Notes. 2014;7:427. Published 2014 Jul 4. doi:10.1186/1756-0500-7-427

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Quellen:
Onur S, Niklowitz P, Jacobs G, et al. Ubiquinol reduces gamma glutamyltransferase as a marker of oxidative stress in humans. BMC Res Notes. 2014;7:427. Published 2014 Jul 4. doi:10.1186/1756-0500-7-427

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Quellen:
Thakur AS, Littarru GP, Funahashi I, Painkara US, Dange NS, Chauhan P. Effect of Ubiquinol Therapy on Sperm Parameters and Serum Testosterone Levels in Oligoasthenozoospermic Infertile Men. J Clin Diagn Res. 2015;9(9):BC01-BC3. doi:10.7860/JCDR/2015/13617.6424

CoQ10 deficiency has been suggested as a factor in complications of hyperthyroidism, including heart failure. Pre-clinical research and a small clinical study indicate CoQ10 supplementation may help improve cardiac performance in those with hyperthyroidism [,,].

Quellen:
Mantle D, Hargreaves IP. Coenzyme Q10 and Endocrine Disorders: An Overview. Antioxidants (Basel). 2023;12(2):514. Published 2023 Feb 17. doi:10.3390/antiox12020514

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Quellen:
Mantle D, Hargreaves IP. Coenzyme Q10 and Endocrine Disorders: An Overview. Antioxidants (Basel). 2023;12(2):514. Published 2023 Feb 17. doi:10.3390/antiox12020514

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Quellen:
Mantle D, Hargreaves IP. Coenzyme Q10 and Endocrine Disorders: An Overview. Antioxidants (Basel). 2023;12(2):514. Published 2023 Feb 17. doi:10.3390/antiox12020514

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Quellen:
Mantle D, Hargreaves IP. Coenzyme Q10 and Endocrine Disorders: An Overview. Antioxidants (Basel). 2023;12(2):514. Published 2023 Feb 17. doi:10.3390/antiox12020514

⇒ 100-200mg Ubichinol tgl.

Quellen:

  • Mantle D, Hargreaves IP. Coenzyme Q10 and Endocrine Disorders: An Overview. Antioxidants (Basel). 2023;12(2):514. Published 2023 Feb 17. doi:10.3390/antiox12020514
  • Palan P.R., Connell K., Ramirez E., Inegbenijie C., Gavara R.Y., Ouseph J.A., Mikhail M.S. Effects of menopause and hormone replacement therapy on serum levels of coenzyme Q10 and other lipid-soluble antioxidants. Biofactors. 2005;25:61–66. doi: 10.1002/biof.5520250107. [PubMed] [CrossRef] [Google Scholar]

⇒ 100mg Ubichinol tgl.

Quellen:

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⇒ 50-100mg Ubichinol tgl.

Quellen:

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